Featured conditions
Viral hemorrhagic (hem-uh-RAJ-ik) fevers are infectious diseases that can cause severe, life-threatening illness. They can damage the walls of tiny blood vessels, making them leak, and can hamper the blood’s ability to clot. The resulting internal bleeding is usually not life-threatening, but the diseases can be.
Some viral hemorrhagic fevers include:
These diseases most commonly occur in tropical areas. In the United States, people who get them usually have recently traveled to one of those areas.
There’s no cure for viral hemorrhagic fevers. There are vaccines for only a few types. Until additional vaccines are developed, the best approach is prevention.
Signs and symptoms of viral hemorrhagic fevers vary by disease. In general, early signs and symptoms can include:
More-severe symptoms include:
The best time to see a doctor is before you travel to a developing country to ensure that you’ve received any available vaccinations and pre-travel advice for staying healthy.
If you develop signs and symptoms once you return home, talk to a doctor, preferably one trained in international medicine or infectious diseases. Tell your doctor where you’ve traveled.
Viral hemorrhagic fevers are spread by contact with infected animals or insects. The viruses that cause viral hemorrhagic fevers live in a variety of animal and insect hosts. Most commonly the hosts include mosquitoes, ticks, rodents or bats.
Some viral hemorrhagic fevers can also be spread from person to person.
Some viral hemorrhagic fevers are spread by mosquito or tick bites. Others are spread by contact with infected body fluids, such as blood, saliva or semen. A few varieties can be inhaled from infected rat feces or urine.
If you travel to an area where a particular hemorrhagic fever is common, you can be infected there but not develop symptoms until after you return home. Depending on the type of virus, it can take from two to 21 days for symptoms to develop.
Living in or traveling to an area where a particular viral hemorrhagic fever is common will increase your risk of becoming infected with that particular virus. Other factors that can increase your risk include:
Viral hemorrhagic fevers can cause:
Preventing viral hemorrhagic fevers is challenging. If you live in, work in or travel to areas where these diseases are common, protect yourself from infection by using appropriate protective barriers when working with blood or body fluids. For example, wear gloves and eye and face shields. Precautions also include careful handling, disinfection and disposal of lab specimens and waste.
The yellow fever vaccine is generally considered safe and effective. However, in rare cases, serious side effects can occur. The yellow fever vaccine isn’t recommended for children younger than 9 months of age; pregnant women, especially during the first trimester; or people with compromised immune systems.
There’s also an Ebola vaccination that protects against one type of Ebola. Check with the Centers for Disease Control and Prevention about the status of the countries you’re visiting — some require certificates of vaccination for entry.
Do your best to avoid these insects, especially when traveling in areas where there are outbreaks of viral hemorrhagic fevers. Wear light-colored long pants and long-sleeved shirts or, better yet, permethrin-coated clothing. Don’t apply permethrin directly to the skin.
Avoid being outside, if possible, at dusk and dawn when mosquitoes are most active, and apply mosquito repellent with a 20% to 25% concentration of DEET to your skin and clothing. If you’re staying in tented camps or in hotels, use bed nets and mosquito coils.
If you live where there are outbreaks of viral hemorrhagic fevers, take steps to keep rodents out of your home:
Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission.
Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press.
Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below.
- Terms and Conditions
- Privacy Policy
- Notice of Privacy Practices
- Notice of Nondiscrimination
- Manage Cookies
A single copy of these materials may be reprinted for noncommercial personal use only. “Mayo,” “Mayo Clinic,” “MayoClinic.org,” “Mayo Clinic Healthy Living,” and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.
This site complies with the HONcode standard for trustworthy health information:
verify here.